麻豆视频

IMAGE CAPTION: Laurel Gibson, a PhD student in the Department of Psychology and Neuroscience, asks ultramarathon runner Heather Mashhoodi questions as part of a new study exploring how marijuana influences exercise. Study participants are exempted from the indoor mask requirement while听on the treadmill.听 Credit: Patrick Campbell/CU Boulder

As an ultramarathoner who covers as many as 100 miles a week during peak training, Heather Mashhoodi has to get creative to make the miles go by faster.

She listens to podcasts and audio books and takes in the natural beauty. And when her enthusiasm begins to wane mid-run, she pops half of a marijuana-infused gummy into her mouth.

鈥淲hen I run for a really long time, this thing naturally kicks in and it makes the colors brighter and makes my thoughts clearer and makes me more emotionally in tune,鈥� says Mashhoodi, 31. 鈥淲hen I use cannabis and run, I get to feel that at a little less intense mileage.鈥�

Mashhoodi is among a growing number of athletes mixing weed with workouts, either to spark motivation, ease recovery or find more enjoyment in exercise.

With a lack of research, scientists are unsure just how Tetrahydrocannabinol (THC) and cannabidiol (CBD) 鈥� the two primary active ingredients in marijuana鈥攊nfluence physical activity. But in the wake of the Olympic suspension of sprinter Sha鈥機arri Richardson for testing positive for marijuana (a banned substance under World Anti-Doping Agency rules), the question has become a matter of much scientific debate: Does cannabis enhance or hinder performance? Or both? And if so, how?

A new first-of-its-kind study at CU Boulder aims to shed light.

鈥淭o date, there are no human studies on the effects of legal market cannabis on the experience of exercise,鈥� said Laurel Gibson, a PhD student in the Department of Psychology and Neuroscience and principal investigator of the study. 鈥淭hat鈥檚 where we come in.鈥�

Running in SPACE

The SPACE study (Study on Physical Activity and Cannabis Effects) will enlist more than 50 paid adult volunteers who already mix cannabis and exercise for a study involving three sessions. In the first, researchers measure heart rate, have subjects answer a questionnaire and take some baseline fitness measurements. Then, participants are assigned to go to a local dispensary and pick up either a specific CBD-dominant strain or THC-dominant strain.

On one follow up visit, they return, sober, to run on the treadmill for 30 minutes, answering questions every 10 minutes to assess things like their perception of the passage of time, how hard the workout feels, what they鈥檙e thinking about, and how much pain they鈥檙e in. On another visit, they do the same, only they get high before they come.

Federal law prohibits the possession or distribution of marijuana on college campuses, so subjects take it at home, before a researcher picks them up in a mobile laboratory 鈥� a white Dodge Sprinter van sometimes referred to as the 鈥榗annavan鈥欌�� and brings them safely to the lab. Another precautionary measure: The runner wears a black safety belt around his or her waist on the treadmill.

By comparing sober sessions to sessions including cannabis, Gibson and her colleagues hope to make sense of a perplexing contradiction in cannabis research.

鈥淐annabis is often associated with a decrease in motivation鈥� that stereotype of couch-lock and laziness,鈥� said Gibson. 鈥淏ut at the same time, we are seeing an increasing number of anecdotal reports of people using it in combination with everything from golfing and yoga to snowboarding and running.鈥�

One CU Boulder study found that 80% of cannabis users mix weed and working out, with 70% saying it increases enjoyment, 78% saying it boosts recovery and 52% saying it motivates them. Curiously, another study of older adults found that those who used marijuana got more exercise than those who didn鈥檛.

鈥淎s we get older, exercise starts to hurt, and that is one reason older adults don鈥檛 exercise as much,鈥� said Angela Bryan, a professor of psychology and neuroscience and Gibson鈥檚 faculty advisor on the SPACE study, noting that cannabinoids have anti-inflammatory and analgesic properties. 鈥淚f cannabis could ease pain and inflammation, helping older adults to be more active, that could be a real benefit.鈥�

New take on runner鈥檚 high

Even more intriguing, some studies suggest that it is not endorphins that are responsible for the famous 鈥渞unner鈥檚 high鈥� but rather endogenous cannabinoids, naturally produced cannabinoid-like brain chemicals that kick in after a period of exercise, binding to receptors in the brain to make us euphoric and alert. By ingesting CBD or THC, which bind to those same receptors, athletes might, as Mashhoodi describes, enhance or get a head start on that good feeling.

鈥淚t is possible that exogenous cannabinoids like THC or CBD might activate the endocannabinoid system in a way that mimics the runner鈥檚 high,鈥� said Gibson.

The researchers are quick to note that cannabis is also associated with negative effects, including paranoia, confusion and anxiety. They鈥檒l be looking for those effects, too.

Ultimately, they hope their findings can help inform discussions everywhere from doctors鈥� offices to the governing bodies of sport, which will soon be re-evaluating whether marijuana should remain listed as a 鈥渂anned substance鈥� in part because of its potential to enhance performance.

Mashhoodi, one of the first to sign up for the study, said she鈥檚 skeptical that cannabis provides any performance benefit. She said she does not run faster or farther when she鈥檚 stoned. But she feels less joint pain and, psychologically, the benefits are clear.

She鈥檚 eager to see what the study reveals.

鈥淭o me it鈥檚 just exciting to participate,鈥� Mashhoodi said. 鈥淲e know so little and there is so much we need to learn.鈥�

To learn more about the SPACE study, or volunteer, visit the study website.

听