Sleeping just five hours a night over a workweek and having unlimited access to food caused participants in a new study led by the 麻豆视频 to gain nearly two pounds of weight.
The study, performed in collaboration with the CU Anschutz Medical Campus, suggests that sufficient sleep could help battle the obesity epidemic.
鈥淚 don鈥檛 think extra sleep by itself is going to lead to weight loss,鈥� said Kenneth Wright, director of CU-Boulder鈥檚 Sleep and Chronobiology Laboratory, which led the study. 鈥淧roblems with weight gain and obesity are much more complex than that. But I think it could help. If we can incorporate healthy sleep into weight-loss and weight-maintenance programs, our findings suggest that it may assist people to obtain a healthier weight.鈥澨� But further research is needed to test that hypothesis, Wright added.
Previous research has shown that a lack of sleep can lead to weight gain, but the reasons for extra pounds were unclear. In the new study, published March. 11 in the Proceedings of the National Academy of Sciences, the researchers show that, while staying awake longer requires more energy, the amount of food study participants ate more than offset the extra calories burned.
鈥淛ust getting less sleep, by itself, is not going to lead to weight gain,鈥� Wright said. 鈥淏ut when people get insufficient sleep, it leads them to eat more than they actually need.鈥�
For the study, researchers monitored 16 young, lean, healthy adults who lived for about two weeks at the University of Colorado Hospital, which is equipped with a 鈥渟leep suite鈥� for controlling sleep opportunities 鈥� by providing a quiet environment and by regulating when the lights are on and off 鈥� and a sealed room that allows researchers to measure how much energy participants are using based on the amount of oxygen they breathe in and the amount of carbon dioxide they breathe out.
All participants spent the first three days with the opportunity to sleep nine hours a night and eating meals that were controlled to give participants only the calories they needed to maintain their weight in order to establish baseline measurements. But after the first few days, the participants were split into two groups: one that spent five days with only five hours to sleep in and one that spent five days with nine hours of sleep opportunity. In both groups, participants were offered larger meals and had access to snack options throughout the day ranging from fruit and yogurt to ice cream and potato chips. After the five-day period, the groups switched.
On average, the participants who slept for up to five hours a night burned 5 percent more energy than those who slept up to nine hours a night, but they consumed 6 percent more calories. Those getting less sleep also tended to eat smaller breakfasts but binge on after-dinner snacks. In fact, the total amount of calories consumed in evening snacks was larger than the calories that made up any individual meal.听 The current findings add to the growing body of evidence showing that overeating at night may contribute to weight gain.
鈥淲hen people are sleep-restricted, our findings show they eat during their biological nighttime when internal physiology is not designed to be taking in food,鈥� said Wright, who is already working on a new study to better determine the implications of when people are eating not just what they鈥檙e eating.
Wright and his colleagues also found that men and women responded differently to having access to unrestricted food. Men gained some weight even with adequate sleep when they could eat as much as they wanted, while women simply maintained their weight when they had adequate sleep, regardless of how much food was available. Both men and women gained weight when they were only allowed to sleep for up to five hours.
Other co-authors of the new study include Rachel Markwarld and Mark Smith, who were both postdoctoral researchers in Wright鈥檚 lab, as well as School of Medicine faculty members Edward Melanson, Leigh Perreault, Robert Eckel and Janine Higgins from the Anschutz Medical Campus.
The research was funded with grants from the National Institutes of Health, the Colorado Clinical and Translational Sciences Institute, and the Howard Hughes Medical Institute in collaboration with the Biological Sciences Initiative and CU-Boulder鈥檚 Undergraduate Research Opportunities Program.
Contact:
Kenneth Wright, 303-735-1923
Kenneth.wright@colorado.edu
Laura Snider, CU media relations, 303-735-0528
Laura.Snider@colorado.edu
