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Starting at top left: 1) AFM image of two molecules of DNA polymerase-alpha bound to DNA (); 2) High voltage EM image of axoneme (); 3) Fast-frozen EM image of Golgi stack (); 4) Engineered tissue used as skin substitute (); 5) Engineered orthopedic biomaterial designed to enhance tissue regeneration for patients withbone loss (); 6) Mammalian PtK1 cell in prophase, showing condensed chromosomes (blue) with the MAP kinase ERK2 (red) at the kinetichores. Inset is expanded view of two chromosomes ().