Climate Change and Infectious Disease

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Does warming lead to more disease?

Climate change is projected to influence the dynamics and distributions of many parasitic diseases of both humans and wildlife. Whether such changes will serve to increase or reduce disease depends on the differential thermal physiologies of parasites and their hosts. Available forecasts suggest that climate change will involve changes in both mean temperature and temperature variability, yet relatively little is known about how shifts in temperature affect parasite-host relationships.

The Project

With an emphasis on trematode parasites as a model system, we are combining experimental-based approaches both in the laboratory and in mesocosms with metabolic theory to develop a more predictive framework for how climate shifts will affect disease risk by different types of parasites (see Paull and Johnson 2011, Paull et al. 2012, Hoverman et al. 2013, Altizer et al. 2013). Concurrently, we are also using long-term data from small pond ecosystems in California to explore how changes in precipitation influence interactions between hosts and parasites. For instance, the recent megadrought in California, which is estimated to be among the most severe in the last 1,000 years, dramatically altered patterns of parasite richness, infection prevalence, and host pathology. This ‘natural experiment’ and the system’s subsequent response have provided a powerful opportunity to test hypotheses about the direct and indirect effects of drought on entire host-parasite assemblages.

Project publications

Altman, K. A., Paull, S. H., Johnson, P. T. J., Golembieski, M. N., Stephens, J. P., LaFonte, B. E., and T. R. Raffel (2016). Host and parastie thermal acclimation responses depend on the stage of infection.ÌýJournal of Animal EcologyÌý85: 1014-2014.ÌýÌý

Paull, S. H., Raffel, T. R., LaFonte, B. E. and P. T. J. Johnson (2015). How temperature shifts affect parasite production: Testing the roles of thermal stress and acclimation.ÌýFunctional EcologyÌý29: 941–950.ÌýÌý

Koprivnikar, J., Paull, S. H. and P. T. J. Johnson (2014). Combined influence of hydroperiod and parasitism on larval amphibian development.ÌýFreshwater ScienceÌý33: 941-949.ÌýÌý

Paull, S. H. and P. T. J. Johnson (2014). Experimental warming drives a seasonal shift in the timing of host-parasite dynamics with consequences for disease risk.ÌýEcology LettersÌý17: 445-453.ÌýÌý

Rohr, J. R., Blaustein, A. R., Paull, S. H., Johnson, P. T. J., Raffel, T., and S. Young (2013). Using physiology to understand climate-driven changes in disease and their implications for conservation.ÌýConservation PhysiologyÌý1: doi:10.1093/conphys/cot022.ÌýÌýÌý PDF

Altizer, S., Ostfeld, R. S., Harvell, C. D., Johnson, P. T. J., and S. Kutz (2013). Climate change and infectious diseases: from evidence to a predictive framework.ÌýScienceÌý341: 514-519.ÌýÌý

Paull, S. H., LaFonte, B., and P. T. J. Johnson (2012). Temperature-driven shifts in a host-parasite interaction drive nonlinear changes in disease risk.ÌýGlobal Change BiologyÌý18: 3558-3567.ÌýÌý

Hoverman, J. T., Paull, S. H., and P. T. J. Johnson (2013). Does climate change increase the risk of disease? Analyzing published literature to detect climate–disease interactions. In Pielke, R. Sr. (ed.),ÌýClimate Vulnerability: Understanding and Addressing Threats to Essential Resources, Vol. 4., Academic Press. DOI:Ìý

Paull, S. and P. T. J. Johnson (2013). Can we predict climate-driven changes to disease dynamics?Ìý Applications for theory and management in the face of uncertainty.ÌýWildlife Conservation in a Changing ClimateÌý(J. F. Brodie, E. Post and D. Doak, eds.). University of Chicago Press.ÌýÌýÌý

Blaustein, A. R., Gervasi, S. S., Johnson, P. T. J., Hoverman, J. T., Belden, L. K., Bradley, P. W. and G. Y. Xie (2012). Ecophysiology meets conservation: understanding the role of disease in amphibian population declines.ÌýÌýPhilosophical Transactions of the Royal Society, Series BÌý367: 1688-1707.ÌýÌý

Rohr, J. R., Johnson, P. T. J., Paull, S. H., Raffel, T. R., Dobson, A. P., Kilpatrick, A. M., Ruiz-Moreno, D., Pascual, M. and M. B. Thomas (2011). Frontiers in climate change-disease research.ÌýTrends in Ecology and EvolutionÌý26: 270-277.ÌýÌý

Paull, S. and P. T. J. Johnson (2011). High temperature enhances host pathology in a snail-trematode system: possible consequences of climate change for the emergence of disease.ÌýFreshwater BiologyÌý56: 767-778.ÌýÌý

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