David Nesbitt
Adjoint Professor
Biochemistry
djn@jila.colorado.edu
303-492-8857

Office: JILA A805
尝补产:听JILA B212, B214, B217, B219, B221, X120

Education

Ph.D.:听University of Colorado, 1981
Postdoctoral Fellow:听National Research Fellow at National Bureau of Standards, 1981-82

Areas of Expertise

Instrument Development, Bioanalytical Chemistry, Molecular Biophysics, Atmospheric/Astrochemistry, Biophysics, Kinetics/Thermochemistry

Awards and Honors

Fellow, American Academy of Arts and Sciences, 2013; Fellow, American Chemistry Society, 2010; Presidential Rank Award, Department of Commerce, 2009; Fellow, Royal Society of Chemistry (UK), 2005; NIST Fellow, National Institute of Standards and Technology, 2005; Bourke Medal, Royal Society of Chemistry, Faraday Division, 2002; Alexander von Humboldt Fellowship, 1999; William F. Meggers Award, Optical Society of America, 1999; Earle K. Plyler Prize, 1997; Edward Uhler Condon Award, 1995; Department of Commerce Silver Medal, 1992; Arthur S. Fleming Award, 1991; Fellow, American Physical Society, 1991; Wilson Prize Lecture (Harvard University) , 1989; Alfred P. Sloan Fellow, 1987; Dreyfus Foundation Grant for Newly Appointed Faculty in Chemistry, 1984; ACS Nobel Laureate Signature Award, 1983

Laser Studies of Spectroscopy, Reaction Dynamics and Single Molecule Microscopy: Chemical Physics, Nanomaterials and Biophysics

The Nesbitt Laboratory pursues research in four main areas:

The group's work involves extensive use of state-of-the art cw and ultrafast pulsed laser technology, nonlinear generation of tunable mid and near-infrared laser light, fast analog electronics, scan probe methods, confocal microscopy, servo-loop control, shaped supersonic expansions, plasma discharges, kinetic analysis and ab initio quantum theoretical calculations. A central unifying goal of the research program is the elucidation of fundamental kinetics and dynamics of elementary chemical/biophysical processes from both experimental and theoretical perspectives.

Professor Nesbitt is a听, a听Physicist at the National Institute of Standards and Technology (), a Full Professor in the听听and a Lecturer in the听.

J. L. Fiore, E. D. Holmstrom and D. J. Nesbitt, "An entropic origin of Mg+2鈥揻acilitated RNA folding," Proc. Nat. Acad. Sci.听109, 2902-2907 (2012).

J. R. Roscioli, D. Bell, and D. J. Nesbitt, "State-resolved velocity map imaging of surface鈥搒cattered molecular flux," Phys. Chem. Chem. Phys.听14, 4013-4304 (2012).

E. D. Holmstrom, J. L. Fiore and D. J. Nesbitt, "Thermodynamic Origins of Monovalent-Facilitated RNA Folding," Biochemistry听51, 3732-3743 (2012).

M. P. Ziemkiewicz, A. Zutz, and D. J. Nesbitt, "Inelastic scattering of radicals at the gas-ionic liquid interface:听 Probing surface dynamics of [bmim][Cl], [bmim][BF4], and [bmim][Tf2N] by rovibronic scattering of NO [2P1/2(0.5)]," J. Phys. Chem. C.听听(2012)

M. A. Roberts, C. Savage, F. Dong, E. N. Sharp-Williams, A. B. McCoy, and D. J. Nesbitt, "Sub-Doppler Infrared Spectroscopy of CH2D Radical in a Slit Supersonic Jet: Isotopic Symmetry Breaking in the C-H Stretching Manifold," J. Chem. Phys.听136, 234308 (2012).

A. W. Gisler and D. J. Nesbitt, "On Probing Ions at the Gas-Liquid Interface by Quantum State-Resolved Molecular Beam Scattering: The Curious Incident of the Cation in the Night Time," Faraday Disc.听157, 听297-305 听听doi: 10.1039/c2fd20026k (2012).

D. J. Nesbitt, "Toward state-to-state dynamics in ultracold collisions: Lessons from high resolution spectroscopy of weakly bound molecular complexes," Chem. Rev.听听(2012).

A. Grubisic, E. Ringe, C. M. Cobley, Y. Xia, L. D. Marks, R. P. Van Duyne, and D. J. Nesbitt, "Plasmonic Near Electric Field Enhancement Effects in Ultrafast Photoelectron Emission: Correlated Spatial and Laser Polarization Microscopy Studies of Individual Ag Nanocubes," Nano Lett. 听听听 (2012).

M.听 A. Roberts, E. N. Sharp-Williams, and D. J. Nesbitt, "High-Resolution Direct-Absorption Spectroscopy of Hydroxymethyl Radical in the CH Symmetric Stretching Region," J. Phys. Chem. A听117听, 7042-7049 听听DOI: 10.1021/jp312877k (2013)

N. F. Dupuis, E. D. Holmstrom, D. J. Nesbitt, "Single Molecule Kinetics Reveal Cation Promoted DNA Duplex Formation Through Ordering of Single Stranded Helices," Biophys. J.听105, 756-766, DOI: 10.1016/j.bpj.2013.05.061 (2013).

C.-H. Chang, G. T. Buckingham and D. J. Nesbitt, "Sub-Doppler Spectroscopy of听trans-HOCO Radical in the OH Stretching Mode," J. Phys. Chem. A,听117, 13255-13264 DOI:听(2013).

K. T. Early and D. J. Nesbitt, "Size-dependent Photoionization in Single CdSe/ZnS Nanocrystals," Nano Lett听13, 4844-4849听听(2013)

E. D. Holmstrom, N. F. Dupuis, and D. J. Nesbitt, "Single-Molecule Pulsed Infrared听Heating Studies of DNA Duplex Dissociation," Biophys. J. 106, 220-231听听(2014).